Agenda
Wednesday, September 10 | |
3:00-6:00 | Registration / Opening Night Reception |
Thursday, September 11 | |
7:00-8:00 | Breakfast |
8:00-8:10 | Don Fitzgerald, Roche Colorado Corporation Welcome |
8:10-8:15 | Ralph DiLibero, Roche Colorado Corporation Housekeeping |
Peptides in the Clinic | |
8:15-9:00 | Angelika Fretzen, Ironwood Pharmaceuticals Linaclotide, a First-in-Class Guanylate Cyclase C Agonist in Development for the Treatment of Irritable Bowel Syndrome with Constipation and Chronic Constipation |
9:00-9:45 | Bruce Morimoto, Allon Therapeutics Neuroprotection by AL-108; A Case Study for Development of a CNS-Active Peptide as a Treatment for Alzheimer’s Disease |
9:45-10:00 | Coffee Break |
10:00-10:45 | Richard Duke, Apoplogic Pharmaceuticals Breceptin: Pre-Clinical Data and Clinical Development Plans for a Peptide-Based Bradykinin Antagonist in Small Cell Lung Cancer |
10:45-11:30 | Soren Kjareluff, Novozymes NZ2114 Plectasin, a New Antibiotic for Treatment of Resistant Gram Positive Bacterial Infections |
11:30-11:50 | Panel Discussion |
| 11:50-1:00 | Lunch |
Emerging Technologies | |
1:00-1:45 | Paul Wentworth, Scripps / Oxford A Chemical Link Between Inflammation and Protein Misfolding Diseases |
1:45-2:30 | Richard Dimarchi, Indiana University The Emergence of Chemical Biotechnology and It’s Application to Optimization of Endocrine Hormones |
2:30-3:00 | Coffee Break |
3:00-3:45 | Gunnar Kaufmann, Scripps Research Institute Bacterial Quorum Sensing as Target for Anti-Infective Therapy |
3:45-4:30 | Soumitra Ghosh, Amylin Pharmaceuticals Integrated Neurohormonal Therapy for Obesity |
4:30-4:50 | Panel Discussion |
6:00-10:00 | Dinner at Red Lion Restaurant |
Meienhofer Award Presented by John Tayer, Roche Colorado Waleed Danho, Hoffmann-La Roche | |
Friday, September 12 | |
7:00-8:00 | Breakfast |
Analytical and Biophysical Methods | |
8:00-8:45 | John H. A. Amery, Pfizer An Industry Perspective on the Use of Bioassays for Synthetic Peptide and Nucleotide Pharmaceuticals |
8:45-9:30 | Ted Randolph, University of Colorado Conformational and Colloidal Contributions to Stability against Aggregation of Proteins |
9:30-10:00 | Coffee Break |
Synthetic Methodology | |
10:00-10:45 | Rashia Turner, University of Califonia Santa Cruz Using Click Chemistry to Synthesize and Study the Relative Permeabilities of Cyclic Peptides and Their Linear Precursors |
10:45-11:30 | Robert P. Hammer, Louisiana State University Amino Acid Analogues in the Design of Functional Peptide Mimics |
11:30-11:50 | Panel Discussion |
| 11:50-1:00 | Lunch |
1:00-1:45 | Chris Roberts, Roche Colorado Corporation Development and Scale-Up of an MC-4 Agonist |
Peptides in the Clinic 2 | |
1:45-2:30 | Les Mirand, Amgen Pharmaceuticals Identification of Potent, Selective and Metabolically Stable Peptide Antagonists to the Calcitonin Gege-Related Peptide (CGRP) Receptor |
2:30-3:00 | Coffee Break |
3:00-3:45 | Claudio Mapelli, Bristol-Myers Squibb A novel Class of 11-MER Peptide Agonist of the GLP-1 Receptor |
3:45-4:30 | Christian Elling, 7TM Pharma Development of Y2 and Y4 GI-Tract Satiety Signals as Anti-Obesity Agents |
4:30-4:50 | Panel Discussion |
5:00-8:00 | Cocktail Reception and Poster Session |
Presenting Sponsor